During the Imamate of Imam Hassan Aly, Ismaili dawat spread to Turkey, Armenia, and Crimea (Aziz, 1974). According to his will, he was buried in Najjaf, Iraq, after ruling as Imam of the Time for thirty-five years. He was followed in succession by his son Imam Qassim Ali (Aziz, 1974).

Mowlana Sayed Ali, also known as Shah Ismail, Agha Hasan Shah and Shah Abul-Hasan Baig, shifted his primary residence from Kahek to Kerman, after being offered governorship of the province by the Safawi court (Aziz, 1974). After appointing his son, Hasan Ali, to the Throne of Imamate, Imam Sayed Ali passed away in Kerman in 1661 AD (Sadik Ali, 1997).

Mowlana Imam Nizar rebuilt the city of Kahek and shifted his residence hereto from Anjudan (Aziz, 1974). An Ismaili dai, and a descendent of Pir Sadirdeen, by the name of Sayed Abdul Nabi, lived during this period in India and preached mostly in Gujrat. Imam Nizar passed away in Kahek, his body buried in his palace, which served as a mausoleum also for other members of the Imam's family. (Sadik Ali, 1997).

The last Imam to live in Anjudan, Imam Khalilillahi Ali remained aloof from the political instability which prevailed throughout Iran at this time. During this time, Pir Naseer Mohammed was followed by Pir Agha Hashem in the line of Piratan. Sayyid Daood, an acclaimed vakil, was appointed by the Imam to govern the religious affairs in the jamats of India. The Imam was followed in succession by his son Sayyid Nizar Ali in 1585.

After the death of his father, Pir Qasim Shah bin Pir Alauddin, Pir Naseer Muhammed was appointed to Piratan by Imam Nooruddin Ali. He was the 33rd Pir of the Ismailis. During the Imamate of Imam Nooruddin Ali, the devout Ismaili poet, Khaki Khorasani was imprisoned by the Mogul king Humayoon of India, and died in prison (Aziz, 1974). The Imam passed away in Anjudan and consigned the office of Imamate to his son, Khalilillahi Aly.

Imam Nooriddeen Aly was born in 1513AD in Anjudan, and succeeded his father to the Throne of Imamate in the year 1518AD at the age of five years.

The Imamate of Imam Zilfiqar Ali lasted a short while, a period of two years alone. The Safavids lost their foothold in Iran during this time, allowing the Ismailis to enjoy a greater sense of religious freedom and expression (Aziz, 1974). A famous Ismaili poet, Khaki Khorasani became a devout follower of the Imam as early as age seven, with his poetry bearing testimony of the piety and devotion of the Ismailis to their Imam (Sadik Ali, 1997).

Because of his mother Sabra Khatoon, a Safawi princess, Imam Murad Meerza enjoyed cordial relations with the royal Safavid family. The Imam was extremely respected and loved, and as such, a world of opportunities were offered to the Ismailis in small trade, farming, military and civil services (Aziz, 1974). Imam Murad Meerza passed away in Anjudan and was succeeded by his son Zilfiqar Aly (Sadik Ali, 1997).

During the Imamate of Imam Abizzar Aly, the rise of the Safavid Empire in Iran posed significant risk to the lives of the Ismailis. Announcing Shiism as the state religion, the Safavids sought to set themselves apart from the neighboring Sunni Ottamans. However, this adoption was far from tolerant, and Sufis, Ismailis, and other smaller sects of the Muslim faith found themselves prey to execution by the Safavids. Hence, in these turbulent times too, the Ismailis practiced taqiyah, often assuming the cloak of Twelver Shiism (Sadik Ali, 1997).

Soon after the ascension of Imam Ghareeb Mirza, the headquarters of the Imamate shifted to Anjudan, a move that would prove to be beneficial to all Ismailis all over Iran. The Imam kept himself out of the sphere of politics, and lived a private life until his death in 1498 AD.